Rebooted neurons halt brain degeneration in mice
Mice with a form of dementia have had the condition reversed by a process that involves ‘rebooting’ brain cells otherwise destined to die.
The process that kills the cells could be common to all dementias, so blocking it in the same way might hold promise for Alzheimer’s disease and Parkinson’s disease – although more research is needed to explore this further.
“This is potentially a common pathway in all these diseases,” says Giovanna Mallucci at the University of Leicester, UK. “The key thing is that we’ve moved away from a disease-specific mechanism to a more generic cause of cell death,” she says.
Mallucci and colleagues treated mice that were bred to develop a form of prion disease similar to mad cow disease and Creutzfeldt-Jakob disease. Misfolded prion proteins accumulate in cells, forming dense plaques that clog up the brain and kill brain cells in the process. Read More
Posted on May 6, 2012, in #breaking news, #technology and tagged creutzfeldt jakob disease, mad cow disease, medicine, prion proteins, science, studies, university of leicester uk. Bookmark the permalink. Leave a comment.